RT Book, Section A1 Gilligan, Timothy A2 Chabner, Bruce A. A2 Longo, Dan L. SR Print(0) ID 1127648736 T1 Testicular Cancer T2 Harrison's Manual of Oncology, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071793254 LK hemonc.mhmedical.com/content.aspx?aid=1127648736 RD 2024/04/18 AB Although testis cancer is rare when viewed across the lifespan, it is the most common malignancy in men aged 20–35 years. Thanks to the high cure rate of the disease, however, it represents fewer than 5% of cancer deaths during those ages. In 2013, there were about 7,920 new cases and 370 deaths from testicular cancer. Incidence is relatively stable while mortality has been in decline. The declining mortality rate is attributed to the development of curative chemotherapy for advanced disease, improved treatment algorithms, earlier stage at presentation, and a growing proportion of seminomas relative to nonseminomas. The U.S. male lifetime risk of being diagnosed with testis cancer is between 3 and 4 in 1000. Testis cancer is exceedingly rare in African American men, whose incidence of the disease is one-fifth that of white Americans.