RT Book, Section A1 Fojo, Tito A2 Chabner, Bruce A. A2 Longo, Dan L. SR Print(0) ID 1127650027 T1 Adrenocortical Cancer T2 Harrison's Manual of Oncology, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071793254 LK hemonc.mhmedical.com/content.aspx?aid=1127650027 RD 2024/10/06 AB Adrenocortical carcinoma (ACC) is a rare malignancy, affecting 1.5–2 persons per million each year (1). ACC is slightly more common in women and has a bimodal age distribution, with a higher incidence in children younger than 5 years and in adults in their 4th and 5th decades of life (1). Despite improved methods of diagnosis, ACC usually presents at an advanced stage and as a result 5-year survival ranges from 20% and 45%.