RT Book, Section A1 Jawed, Irfan A1 Marshall, John A2 Boyiadzis, Michael M. A2 Frame, James N. A2 Kohler, David R. A2 Fojo, Tito SR Print(0) ID 1128251477 T1 Anal Cancer T2 Hematology-Oncology Therapy, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071637893 LK hemonc.mhmedical.com/content.aspx?aid=1128251477 RD 2024/03/28 AB EpidemiologyTable Graphic Jump Location|Download (.pdf)|PrintEpidemiologyIncidence:7,210 (male: 2,660; female: 4,550. Estimated new cases for 2014 in the United States)Stage at Presentation1.5 per 100,000 male per year, 1.9 per 100,000 femaleStages I/II:50%Deaths:Estimated 950 in 2014 (male: 370; female: 580)Stage III:29–40%Median age at diagnosis:60 yearsStage IV:10–13%Male to female ratio:Slight female predominance Daling JR et al. J Natl Cancer Inst 2000;92:1500–1510Fred Hutchinson Cancer Research Center, Changing Trends in Sexual Behavior May Explain Rising Incidence of Anal Cancer Among American Men and Women. Fred Hutchinson Cancer Research Center (fhcrc.org). 2004-07-06. Retrieved 2010-04Frisch M et al. Gynecol Oncol 2009;114:395–398Maggard MA et al. Dis Colon Rectum 2003;46:1517–1523; discussion 1523–1524; author reply 1524Ryan DP et al. Int J Cancer 2010;127:675–684Ryan DP et al. N Engl J Med 2000;342:792–800Siegel R et al. CA Cancer J Clin 2014;64:9–29Surveillance, Epidemiology and End Results (SEER) Program, available from http://seer.cancer.gov (accessed in 2013)Uronis HE and Bendell JC. Oncologist 2007;12:524–534