RT Book, Section A1 DeAngelis, Lisa M. A1 Wen, Patrick Y. A2 Longo, Dan L. SR Print(0) ID 1128357764 T1 PRIMARY AND METASTATIC TUMORS OF THE NERVOUS SYSTEM T2 Harrison's Hematology and Oncology, 2e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071814904 LK hemonc.mhmedical.com/content.aspx?aid=1128357764 RD 2024/04/24 AB Primary brain tumors are diagnosed in approximately 52,000 people each year in the United States. At least half of these tumors are malignant and associated with a high mortality rate. Glial tumors account for about 60% of all primary brain tumors, and 80% of those are malignant neoplasms. Meningiomas account for 25%, vestibular schwannomas 10%, and central nervous system (CNS) lymphomas about 2%. Brain metastases are three times more common than all primary brain tumors combined and are diagnosed in approximately 150,000 people each year. Metastases to the leptomeninges and epidural space of the spinal cord each occur in approximately 3–5% of patients with systemic cancer and are also a major cause of neurologic disability in this population.