RT Book, Section
A1 McDevitt, Pamela W.
A1 Fojo, Tito
A2 Boyiadzis, Michael M.
A2 Frame, James N.
A2 Kohler, David R.
A2 Fojo, Tito
SR Print(0)
ID 1128367411
T1 Guidelines for Chemotherapy Dosage Adjustment
T2 Hematology-Oncology Therapy, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071637893
LK hemonc.mhmedical.com/content.aspx?aid=1128367411
RD 2024/04/18
AB Table  Graphic  Jump  Location|Download  (.pdf)|PrintAlphabetical  Listing  of  Drugs  by  both  Generic  (bold)  and  Proprietary  NamesDrug  Names:  Generic  (in  bold)  or  ProprietaryDrug  Names:  Generic  (in  bold)  or  ProprietaryAdjust  if  Function  ImpairedHepaticRenalAbiraterone  acetateZytiga®+−Abraxane®Paclitaxel  protein  bound  particles+−Adcetris™Brentuximab  vedotin−−ado-trastuzumab  emtansineKadcyla™±±Adriamycin®Doxorubicin  HCl+−AfatinibGilotrif±±Afatinib  dimaleateGilotrif™±±Afinitor®Everolimus+±Agrylin®Anagrelide  HCl+−AldesleukinProleukin®−+AlemtuzumabCampath®−−Alimta®Pemetrexed  disodium−±AlitretinoinPanretin®−−Alkeran®Melphalan  (orMelphalan  HCl)−+AltretamineHexalen®−−AmifostineEthyol®−−AminoglutethimideCytadren®−−AmsacrineAmsidine®++Amsidine®Amsacrine++Anagrelide  HClAgrylin®+−AnastrozoleArimidex®+−Aranesp®Darbepoetin  alfa−−Aredia®Pamidronate  disodium±+Arimidex®Anastrozole+−Aromasin®Exemestane−−Arranon®Nelarabine±±Arsenic  trioxideTrisenox™++Arzerra™Ofatumumab−−Asparaginase  (E.  coli  source)Elspar®±±Asparaginase  (Erwinia  chrysanthemi  source)Erwinaze™±±Atralin™Tretinoin++Avastin®Bevacizumab−−AxitinibInlyta®±±AzacitidineVidaza®++Bendamustine  HClTreanda®++BevacizumabAvastin®−−BexaroteneTargretin®±±Bexxar®Tositumomab−±BicalutamideCasodex®±−BiCNU®Carmustine±+Blenoxane®Bleomycin  sulfate±+Bleomycin  sulfateBlenoxane®±+BortezomibVelcade®+±Bosulif®Bosutinib±±BosutinibBosulif®±±Brentuximab  vedotinAdcetris™−−Buserelin  acetateSuprefact®−−BusulfanBusulfex®±−Busulfex®Busulfan±−CabazitaxelJevtana®±±CabozantinibS-malateCometriq™±±Campath®Alemtuzumab−−Camptosar®Irinotecan  HCl+−CapecitabineXeloda®±+Caprelsa®Vandetanib±+CarboplatinParaplatin−AQ®−+CarfilzomibKyprolis™±−CarmustineBiCNU®±+Casodex®Bicalutamide±−CeeNU®Lomustine±+Cerubidine®Daunorubicin  HCl++CetuximabErbitux®−−ChlorambucilLeukeran®±+CisplatinPlatinol®−+CladribineLeustatin®±+ClofarabineClolar®±±Clolar®Clofarabine±±Cometriq™CabozantinibS-malate±±Cosmegen®Dactinomycin±−CrizotinibXalkori®±±Cytadren®Aminoglutethimide−−CytarabineCytosar-U®++Cytarabine  lipid  complex  (liposome)DepoCyt®−−Cytosar-U®Cytarabine++DabrafenibTafinlar±±Dabrafenib  mesylateTafinlar®±±DacarbazineDTIC-Dome®±+Dacogen™Decitabine±±DactinomycinCosmegen®±−Denileukin  diftitoxOntak®−−DenosumabXgeva®±±Darbepoetin  alfaAranesp®−−DasatinibSprycel®±±Daunorubicin  HClCerubidine®++Daunorubicin  citrate  liposomalDaunoXome®++DaunoXome®Daunorubicin  citrate  liposomal++DecitabineDacogen™±±DepoCyt®Cytarabine  lipid  complex  (liposome)−−Dexrazoxane  HClTotect®,  Zinecard®−+DocetaxelTaxotere®+−Doxil®Doxorubicin  HCl  liposomal+−Doxorubicin  HClAdriamycin®+−Doxorubicin  HCl  liposomalDoxil®+−Droxia®Hydroxyurea±+DTIC-Dome®Dacarbazine±+Ellence®Epirubicin  HCl++Eloxatin®Oxaliplatin−+Elspar®Asparaginase  (E.  coli  source)±±Emcyt®Estramustine  phosphate  sodium−−EnzalutamideXtandi®±±Epirubicin  HClEllence®++Epoetin  alfaProcrit®−−Erbitux®Cetuximab−−Eribulin  mesylateHalaven™++Erivedge®Vismodegib±±Erlotinib  HClTarceva®+−Erwinaze™Asparaginase  (Erwinia  chrysanthemi  source)±±Estramustine  phosphate  sodiumEmcyt®−−Ethyol®Amifostine−−Etopophos®Etoposide  phosphate++EtoposideVePesid®++Etoposide  phosphateEtopophos®++Eulexin®Flutamide−−EverolimusAfinitor®+±Evista®Raloxifene  HCl±±ExemestaneAromasin®−−Fareston®Toremifene  citrate−−Faslodex®Fulvestrant+−Femara®Letrozole+−FilgrastimNeupogen®−−FloxuridineFUDR®+±Fludara®Fludarabine±+FludarabineFludara®±+FluorouracilFluorouracil±±FluorouracilFluorouracil±±FluoxymesteroneHalotestin®−+FlutamideEulexin®−−Folotyn®Pralatrexate±±FUDR®Floxuridine+±FulvestrantFaslodex®+−GefitinibIressa®−−Gemcitabine  HClGemzar®+−Gemtuzumab  ozogamicinMylotarg®±−Gemzar®Gemcitabine  HCl+−GilotrifAfatinib±±Gilotrif™Afatinib  dimaleate±±Gleevec®Imatinib  mesylate++Goserelin  acetateZoladex®−−Halaven™Eribulin  mesylate++Halotestin®Fluoxymesterone−+Herceptin®Trastuzumab−−Hexalen®Altretamine−−Hycamtin®Topotecan  HCl−+HydroxyureaDroxia®±+Ibritumomab  tiuxetanZevalin®−−IbrutinibImbruvica+−Iclusig™Ponatinib±±Idamycin®Idarubicin  HCl++Idarubicin  HClIdamycin®++Ifex®Ifosfamide±+IfosfamideIfex®±+Imatinib  mesylateGleevec®++ImbruvicaIbrutinib+−Interferon  alfa-2bIntron®  A−−Inlyta®Axitinib±±Intron®  AInterferon  alfa-2b−−IpilimumabYervoy™−−Iressa®Gefitinib−−IrinotecanCamptosar®+−IsotretinoinSotret®±−Istodax®Romidepsin±±IxabepiloneIxempra®+±Ixempra®Ixabepilone+±Jevtana®Cabazitaxel±±Kadcyla™ado-trastuzumab  emtansine±±Kyprolis™Carfilzomib±±LapatinibTykerb®+−LenalidomideRevlimid®−+LetrozoleFemara®+−Leucovorin  calciumLeucovorin−−LeucovorinLeucovorin  calcium−−Leukeran®Chlorambucil±+Leukine®Sargramostim−−Leuprolide  acetateLupron  Depot®−−Leustatin®Cladribine±+LomustineCeeNU®±+Lupron  Depot®Leuprolide  acetate−−Lysodren®Mitotane−−Marqibo®Vincristine  sulfate  liposome±±Matulane®Procarbazine  HCl−+Mechlorethamine  HClMustargen®−−Megace®Megestrol  acetate−−Megestrol  acetateMegace®−−MekinistTramtetinib±±Mekinist™Trametinib  dimethyl  sulfoxide±±Melphalan  (or  Melphalan  HCl)Alkeran®−+MercaptopurinePurinethol®±+MesnaMesnex®±±Mesnex®Mesna±±MethotrexateMethotrexate++MethotrexateMethotrexate++MitomycinMitozytrex®±+MitotaneLysodren®−−Mitoxantrone  HClNovantrone®±−Mitozytrex®Mitomycin±+Mozobil®Plerixafor−+Mustargen®Mechlorethamine  HCl−−Mylotarg®Gemtuzumab  ozogamicin±−Navelbine®Vinorelbine  tartrate+−NelarabineArranon®±±Neulasta®Pegfilgrastim±−Neumega®Oprelvekin−+Neupogen®Filgrastim−−NeutrexinTrimetrexate  glucuronate±−Nexavar®Sorafenib  tosylate−−Nilandron®Nilutamide+−NilotinibTasigna®+−NilutamideNilandron®+−Nipent®Pentostatin−±Novantrone®Mitoxantrone  HCl±−Nplate®Romiplostim±±ObinutuzumabGazyva±±Octreotide  acetateSandostatin®  LAR®++OfatumumabArzerra™−−Omacetaxine  mepesuccinateSynribo™±±Oncaspar®Pegaspargase−−Oncovin®Vincristine  sulfate+−Ontak®Denileukin  diftitox−−OprelvekinNeumega®−+OxaliplatinEloxatin®−+PaclitaxelTaxol®+−Paclitaxel  protein  bound  particlesAbraxane®+−Pamidronate  disodiumAredia®±+PanitumumabVectibix®−−Panretin®Alitretinoin−−Paraplatin−AQ®Carboplatin−+Pazopanib  HClVotrient™+−PegaspargaseOncaspar®−−PegfilgrastimNeulasta®±−Pemetrexed  disodiumAlimta®−±PentostatinNipent®−±Perjeta®Pertuzumab±±PertuzumabPerjeta®±±Platinol®Cisplatin−+PlerixaforMozobil®−+PomalidomidePomalyst®±±Pomalyst®Pomalidomide±±Ponatinib  HClIclusig™±±PralatrexateFolotyn®±±Procarbazine  HClMatulane®−+Procrit®Epoetin  Alfa−−Proleukin®Aldesleukin−+Provenge®Sipuleucel-T−−Purinethol®Mercaptopurine±+Raloxifene  HClEvista®±±RaltitrexedTomudex®−+RegorafenibStivarga®±±Revlimid®Lenalidomide−+Rituxan®Rituximab−−RituximabRituxan®−−RomidepsinIstodax®±±RomiplostimNplate®±±Sandostatin®  LAR®Octreotide  acetate++SargramostimLeukine®−−Savene™Dexrazoxane  HCl−−Sipuleucel-TProvenge®−−Stivarga®Regorafenib±±Soltamox™Tamoxifen  citrate−−Sorafenib  tosylateNexavar®−−Sotret®Isotretinoin±−Sprycel®Dasatinib±±StreptozocinZanosar®+−Sunitinib  malateSutent®±±Suprefact®Buserelin  acetate−−Sutent®Sunitinib  malate±±Synribo™Omacetaxine  mepesuccinate±±Tabloid®Thioguanine±−TafinlarDabrafenib±±Tafinlar®Dabrafenib  mesylate±±Tamoxifen  citrateSoltamox™−−Tarceva®Erlotinib  HCl+−Targretin®Bexarotene±±Tasigna®Nilotinib+−Taxol®Paclitaxel+−Taxotere®Docetaxel+−Tegafur-uracilUftoral®±−Temodar®Temozolomide±±TemozolomideTemodar®±±TemsirolimusTorisel®+−TeniposideVumon®±±ThalidomideThalomid®−−Thalomid®Thalidomide−−ThioguanineTabloid®±−Thiolex®Thiotepa±−ThiotepaThiolex®±−Tomudex®Raltitrexed−+Topotecan  HClHycamtin®−+Toremifene  citrateFareston®−−Torisel®Temsirolimus+−TositumomabBexxar®−±Totect®Dexrazoxane  HCl−+TrabectedinYondelis®±+Trametinib  dimethyl  sulfoxideMekinist™±±TramtetinibMekinist±±TrastuzumabHerceptin®−−Treanda®Bendamustine  HCl++TretinoinAtralin™++Trimetrexate  glucuronateNeutrexin±−Trisenox™Arsenic  trioxide++Tykerb®Lapatinib+−Uftoral®Tegafur-uracil±−ValrubicinValstar®−−Valstar®Valrubicin−−VandetanibCaprelsa®±+Vectibix®Panitumumab−−Velban®Vinblastine  sulfate+−Velcade®Bortezomib+±VemurafenibZelboraf®±±VePesid®Etoposide++Vidaza®Azacitidine++Vinblastine  sulfateVelban®+−Vincristine  sulfateOncovin®+−Vincristine  sulfate  liposomeMarqibo®±±Vinorelbine  tartrateNavelbine®+−VismodegibErivedge®±±VorinostatZolinza®+−Votrient™Pazopanib  HCl+−Vumon®Teniposide±±Xalkori®Crizotinib±±Xeloda®Capecitabine±+Xgeva®Denosumab±±Xtandi®Enzalutamide±±Yervoy™Ipilimumab−−Yondelis®Trabectedin±+Zaltrap®ziv-aflibercept±±Zanosar®Streptozocin+−Zelboraf®Vemurafenib±±Zevalin®Ibritumomab  tiuxetan−−Zinecard®Dexrazoxane  HCl−−ziv-afliberceptZaltrap®±±Zoladex®Goserelin  acetate−−Zoledronic  AcidZometa®±+Zolinza®Vorinostat+−Zometa®Zoledronic  Acid±+Zytiga®Abiraterone  acetate+−