RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Armitage, James O. SR Print(0) ID 1133362900 T1 Hemoglobinopathies Associated with Unstable Hemoglobin T2 Williams Manual of Hematology, 9e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259642470 LK hemonc.mhmedical.com/content.aspx?aid=1133362900 RD 2024/03/29 AB The unstable hemoglobins discussed here result from a mutation that changes the amino acid sequence of one of the globin chains, leading to instability and precipitation of the hemoglobin molecule.Homotetramers of normal β chains (hemoglobin H) or, less often, γ chains (hemoglobin Bart’s) are also unstable. These hemoglobins are found in α-thalassemia (see Chap. 15).