RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Prchal, Josef T.
A1 Levi, Marcel M.
A1 Burns, Linda J.
A1 Armitage, James O.
SR Print(0)
ID 1133363108
T1 Cryopathic Hemolytic Anemia
T2 Williams Manual of Hematology, 9e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259642470
LK hemonc.mhmedical.com/content.aspx?aid=1133363108
RD 2024/04/19
AB This  type  of  anemia  is  caused  by  autoantibodies  that  bind  red  cells  best  at  temperatures  below  37°C,  usually  below  31°C.It  is  mediated  through  two  major  types  of  “cold  antibody”:  cold  agglutinins  and  Donath-Landsteiner  antibodies.Clinical  features  vary  considerably,  but  in  both  types,  the  complement  system  plays  a  major  role  in  red  cell  destruction.