RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Armitage, James O. SR Print(0) ID 1133363575 T1 Classification and Clinical Manifestations of Monocytes and Macrophages T2 Williams Manual of Hematology, 9e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259642470 LK hemonc.mhmedical.com/content.aspx?aid=1133363575 RD 2024/04/25 AB Classification is difficult because few diseases result solely in disturbance of monocytes.Presence of monocytosis, monocytopenia, or histiocytosis may be an important diagnostic feature and may contribute to functional abnormalities.The terms “macrophage” and “histiocyte” are synonymous.— Macrophage is the correct designation when discussing tissue disorders of the mononuclear phagocyte system.— The latter system is the sum of the marrow, blood and tissue pool of monocytes and macrophages. (The term reticuloendothelial for this system is obsolete.)— For historical reasons, macrophage disorders are referred to by pathologists as a histiocytic disorder or a histiocytosis (eg, Langerhans cell histiocytosis).