RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Armitage, James O. SR Print(0) ID 1133364650 T1 Classification and Clinical Manifestations of the Malignant Lymphoid Disorders T2 Williams Manual of Hematology, 9e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259642470 LK hemonc.mhmedical.com/content.aspx?aid=1133364650 RD 2024/03/29 AB Lymphocyte malignancies comprise a wide spectrum of different morphologic and clinical syndromes.The International Lymphoma Study Group proposed a new classification termed Revised European–American Lymphoma classification, or REAL classification, which was modified in 2001 and updated in 2008 by the World Health Organization (WHO) (see Table 53–1).The REAL/WHO classification makes use of the pathologic, immunophenotypic, genetic, and clinical features to define separate disease entities (Table 53–1).Lymphocytic neoplasms are divided into those derived from B cells, T cells, or natural killer (NK) cells.The immunophenotype and the characteristic cytogenetic and genic abnormalities are also included in Table 53–1.The most common indolent and aggressive lymphocytic neoplasms, based on their usual clinical behavior, are listed in Tables 53–2 and 53–3.