RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Prchal, Josef T.
A1 Levi, Marcel M.
A1 Burns, Linda J.
A1 Armitage, James O.
SR Print(0)
ID 1133364910
T1 Large Granular Lymphocytic Leukemia
T2 Williams Manual of Hematology, 9e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259642470
LK hemonc.mhmedical.com/content.aspx?aid=1133364910
RD 2024/04/25
AB T-cell  large-granular  lymphocytic  (T-LGL)  leukemia  results  from  the  clonal  expansion  of  large  granular  lymphocytes  (LGLs)  with  a  T-cell  (CD3+)  phenotype  and  a  clonal  T-cell  receptor  gene  rearrangement(s).Natural  killer  (NK)-LGL  leukemia  is  a  clonal  expansion  of  LGL  with  a  NK  cell  (CD3–)  phenotype.  It  lacks  convenient  markers  to  determine  clonality,  such  as  antigen  receptor  rearrangements.  (See  Chap.  66.)