RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Prchal, Josef T.
A1 Levi, Marcel M.
A1 Burns, Linda J.
A1 Armitage, James O.
SR Print(0)
ID 1133366117
T1 Inherited Deficiencies of Coagulation Factors II, V, V + VIII, VII, X, XI, and XIII
T2 Williams Manual of Hematology, 9e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259642470
LK hemonc.mhmedical.com/content.aspx?aid=1133366117
RD 2024/04/25
AB Inherited  deficiencies  of  coagulation  factors  other  than  factor  VIII  (hemophilia  A)  and  factor  IX  (hemophilia  B)  are  rare  bleeding  disorders  that  occur  in  most  populations.Patients  are  usually  homozygotes  or  compound  heterozygotes.Factor  XI  and  factor  VII  deficiency  occur  relatively  frequently,  and  other  deficiencies  are  relatively  rare  (Table  81–1).The  severity  of  the  bleeding  disorder  usually  relates  to  the  severity  of  the  factor  deficiency.All  may  be  caused  by  decreased  synthesis  of  a  specific  coagulation  factor,  by  synthesis  of  a  dysfunctional  form  of  the  coagulation  factor,  or  both.Inherited  deficiency  of  a  coagulation  factor  does  not  protect  patients  from  thrombosis.