RT Book, Section A1 Aster, Jon C. A1 Steensma, David P. A2 Aster, Jon C. A2 Bunn, H. Franklin SR Print(0) ID 1175062274 T1 Myeloproliferative Neoplasms and Myelodysplastic Syndromes T2 Pathophysiology of Blood Disorders, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259642067 LK hemonc.mhmedical.com/content.aspx?aid=1175062274 RD 2024/03/28 AB LEARNING OBJECTIVESAfter studying this chapter, you should understand:The pathogenic role of specific tyrosine kinase mutations in various myeloproliferative neoplasms.The role of BCR-ABL in the diagnosis and targeted therapy of chronic myelogenous leukemia.The diagnostic and pathogenic role of JAK2 mutations in polycythemia vera.The diagnostic and pathogenic roles of JAK2, calreticulin and thrombopoietin receptor mutations in essential thrombocytosis and primary myelofibrosisThe pathophysiology and clinical features of the myelodysplastic syndromes.