RT Book, Section A1 Smyth, Elizabeth A1 Cunningham, David A2 Longo, Dan L. SR Print(0) ID 1135229665 T1 Pancreatic Cancer T2 Harrison's Hematology and Oncology, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259835834 LK hemonc.mhmedical.com/content.aspx?aid=1135229665 RD 2024/03/28 AB Pancreatic cancer is the fourth leading cause of cancer death in the United States and is associated with a poor prognosis. Endocrine tumors affecting the pancreas are discussed in Chap. 51. Infiltrating ductal adenocarcinomas, the subject of this Chapter, account for the vast majority of cases and arise most frequently in the head of pancreas. At the time of diagnosis, 85–90% of patients have inoperable or metastatic disease, which is reflected in the 5-year survival rate of only 6% for all stages combined. An improved 5-year survival of up to 24% may be achieved when the tumor is detected at an early stage and when complete surgical resection is accomplished.