RT Book, Section A1 DeAngelis, Lisa M. A1 Wen, Patrick Y. A2 Longo, Dan L. SR Print(0) ID 1135230032 T1 Primary and Metastatic Tumors of the Nervous System T2 Harrison's Hematology and Oncology, 3e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259835834 LK hemonc.mhmedical.com/content.aspx?aid=1135230032 RD 2024/10/04 AB Primary brain tumors are diagnosed in approximately 52,000 people each year in the United States. At least one-half of these tumors are malignant and associated with a high mortality. Glial tumors account for about 30% of all primary brain tumors, and 80% of those are malignant. Meningiomas account for 35%, vestibular schwannomas 10%, and central nervous system (CNS) lymphomas about 2%. Brain metastases are three times more common than all primary brain tumors combined and are diagnosed in approximately 150,000 people each year. Metastases to the leptomeninges and epidural space of the spinal cord each occur in approximately 3–5% of patients with systemic cancer and are also a major cause of neurologic disability.