RT Book, Section
A1 MA, Lichtman
A1 MS, Shafer
A1 RE, Felgar
A1 N, Wang
SR Print(0)
ID 1138039824
T1 Marrow Circulation
T2 Lichtman's Atlas of Hematology 2016
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071602679
LK hemonc.mhmedical.com/content.aspx?aid=1138039824
RD 2024/04/20
AB Graphic  Jump  LocationView  Full  Size||Download  Slide  (.ppt)XII.A.001Marrow  Circulation.  Schematic  of  Marrow  Circulation.  The  arterial  flow  enters  the  marrow  through  the  nutrient  artery.  The  foramen  through  which  it  flows  is  angulated  about  45  degrees;  the  vessels  do  not  enter  and  leave  perpendicular  to  the  bone  surface.  The  nutrient  artery  bifurcates  into  ascending  and  descending  arterial  branches  from  which  originate  the  radial  arteries  that  either  anastomose  with  the  very  small  vessels  in  the  bony  cortex  or  terminate  to  form  the  primary  venous  sinuses.  Note  that  the  blood  in  systemic  arteries  supplying  the  periosteum  can  comingle  with  the  marrow  arterial  circulation  through  the  vessels  in  the  bony  canals.  The  venous  sinuses  anastomose  with  one  another  forming  secondary  and  tertiary  sinuses,  ultimately  becoming  larger  collecting  sinuses  that  drain  into  the  very  large  diameter  central  sinus.  Thereafter,  blood  flows  out  emissary  veins  through  the  cortical  foramen  to  enter  the  systemic  venous  circulation.  Hematopoiesis  occurs  in  the  intersinusoidal  spaces,  sometimes  referred  to  as  the  hematopoietic  cords.  Newly  formed  mature  blood  cells  penetrate  the  sinus  wall  to  enter  the  blood.  Images  XII.A.002-004  show  electron  micrographs  of  the  venous  circulation.