RT Book, Section
A1 Sorensen, Meredith J.
A1 Gauger, Paul G.
A2 Morita, Shane Y.
A2 Balch, Charles M.
A2 Klimberg, V. Suzanne
A2 Pawlik, Timothy M.
A2 Posner, Mitchell C.
A2 Tanabe, Kenneth K.
SR Print(0)
ID 1145758331
T1 Gastrinoma
T2 Textbook of Complex General Surgical Oncology
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071793315
LK hemonc.mhmedical.com/content.aspx?aid=1145758331
RD 2024/04/16
AB Gastrinomas  are  gastrin-secreting  neuroendocrine  tumors  (NETs),  usually  located  in  the  duodenum  or  pancreas,  that  result  in  hypergastrinemia.  This  leads  to  excessive  gastric  acid  secretion  and  the  resultant  clinical  manifestations,  such  as  refractory  PUD  (with  sequelae  like  bleeding,  perforation,  and  obstruction),  gastroesophageal  reflux  disease,  and  diarrhea.1,2  Gastrinomas  are  associated  with  multiple  endocrine  neoplasia  type  1  (MEN-1)  in  about  25%  of  cases  and  occur  sporadically  the  other  three-quarters  of  the  time.2,3