RT Book, Section A1 Ho, Allen S. A1 Ganly, Ian A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145759077 T1 Cancer of the Oral Cavity T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK hemonc.mhmedical.com/content.aspx?aid=1145759077 RD 2024/03/29 AB The oral cavity is the most common site for squamous cell carcinoma (SCC) of the head and neck, a disease that inflicts substantial morbidity and mortality worldwide.1,2 The primary modality of treatment for both index and recurrent cases is surgical resection, though many patients present with advanced stage disease and require a multidisciplinary approach. A number of issues that impact surgical treatment must be considered, including operative access, need for mandibulectomy, need for neck dissection, and the type of reconstruction. Recovery and rehabilitation often require ancillary services that include dental, prosthodontics, physical therapy, as well as speech and swallow therapy. Patients with adverse pathologic features benefit from postoperative radiation; lymph node extracapsular spread or positive surgical margins in particular suggest need for chemoradiation.3 The current diagnosis and management of oral cavity malignancies are reviewed.