RT Book, Section
A1 Revels, Sha'Shonda L.
A1 Reddy, Rishindra M.
A2 Morita, Shane Y.
A2 Balch, Charles M.
A2 Klimberg, V. Suzanne
A2 Pawlik, Timothy M.
A2 Posner, Mitchell C.
A2 Tanabe, Kenneth K.
SR Print(0)
ID 1145759675
T1 Pleural Diseases: Primary and Metastatic Malignancies
T2 Textbook of Complex General Surgical Oncology
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071793315
LK hemonc.mhmedical.com/content.aspx?aid=1145759675
RD 2024/04/18
AB Pleural  malignant  disease  is  a  heterogeneous  group  of  cancers  that  range  from  primary  intrathoracic  cancers  such  as  mesothelioma  to  metastatic  cancers  from  extrathoracic  sources.  Often  found  incidentally,  pleural  malignancies  may  present  as  small  pleural  effusions  or  asymmetric  pleural  thickening  on  a  chest  x-ray  or  CT  scan.  As  disease  progresses,  tumor  may  decrease  lung  compliance  by  entrapment  and  fluid  production  causing  pressure  on  other  structures,  leading  to  symptoms  of  chest  pain,  dyspnea,  and  cough.  Goals  of  care  depend  on  the  type  of  malignancy  (primary  vs.  metastatic)  and  the  ability  to  control  disease  (small  volume  vs.  large  volume).  Curative  treatment  may  be  possible  in  early-stage  primary  pleural  cancers  or  in  select  cases  of  metastatic  metastases,  but  often  palliation  is  the  true  goal  for  most  patients  with  pleural  disease.