RT Book, Section A1 King, Tari A. A1 Reis-Filho, Jorge S. A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145760105 T1 Lobular Carcinoma in Situ and Lobular Neoplasia T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK hemonc.mhmedical.com/content.aspx?aid=1145760105 RD 2024/10/07 AB The term lobular neoplasia (LN) encompasses the entire spectrum of atypical epithelial lesions that originate in the terminal duct-lobular unit (TDLU) of the breast, and are characterized by a population of dyshesive cells, which expand the lobules and acini of the TDLUs, and may involve the terminal ducts in a pattern known as Pagetoid spread.1 These lesions were traditionally described under the terms lobular carcinoma in situ (LCIS) and atypical lobular hyperplasia (ALH), which refer to the degree of involvement of the acinar structures of a given TDLU.