RT Book, Section A1 Bear, Harry D. A1 Arthur, Douglas W. A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145760543 T1 Breast Conserving Therapy for Breast Cancer T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK hemonc.mhmedical.com/content.aspx?aid=1145760543 RD 2024/04/19 AB The beginning of breast conserving therapy (BCT) coincides with the early days of clinical radiotherapy. Geoffrey Keynes, a London surgeon, practiced breast conserving surgery combined with radiotherapy in the 1920s, and Vera Peters, a Toronto radiation oncologist began using a similar approach in the 1930s.1-4 The results, in terms of overall survival, were comparable to contemporaneous radical surgical results. However, this was likely in large part a result of advanced disease at presentation and the lack of any or adequate systemic therapies, resulting in equivalent rates of death that occurred before progression or recurrence of local disease.