RT Book, Section
A1 Lynn, Patricio B.
A1 Keskin, Metin
A1 Garcia-Aguilar, Julio
A2 Morita, Shane Y.
A2 Balch, Charles M.
A2 Klimberg, V. Suzanne
A2 Pawlik, Timothy M.
A2 Posner, Mitchell C.
A2 Tanabe, Kenneth K.
SR Print(0)
ID 1145762934
T1 Metastatic Colorectal Cancer
T2 Textbook of Complex General Surgical Oncology
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071793315
LK hemonc.mhmedical.com/content.aspx?aid=1145762934
RD 2024/04/16
AB Metastasis  is  defined  as  the  spread  of  malignant  cells  from  a  primary  tumor  to  a  distant  organ.  It  is  estimated  that  90%  of  all  cancer  deaths  are  a  result  of  metastasis.1  Colorectal  cancer  (CRC)  can  metastasize  to  regional  lymph  nodes,  liver,  lung,  or  the  peritoneal  surface,  and  less  frequently  to  other  organs  such  as  ovaries,  brain,  and  bone.  While  CRC  with  locoregional  lymphatic  spread  is  categorized  as  stage  III  disease  (5-year  overall  survival  (OS)  70.4%),  CRC  with  spread  to  distant  organs  is  categorized  as  stage  IV—or  metastatic—CRC  (CRCm)  and  carries  a  significantly  worse  prognosis  (5-year  OS  12.3%).2