RT Book, Section A1 Press, Oliver W. A1 Lichtman, Marshall A. A1 Leonard, John P. SR Print(0) ID 1148367335 T1 Frontispiece T2 Williams Hematology Malignant Lymphoid Diseases YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781260117066 LK hemonc.mhmedical.com/content.aspx?aid=1148367335 RD 2023/03/22 AB 1. Transmission electron micrograph (TEM) of a normal blood lymphocyte. 2. Scanning electron micrograph (SEM) of a normal blood lymphocyte. 3. TEM of Sézary cell in a patient with the erythrodermic type of cutaneous T-cell lymphoma. Note the cell's characteristic profoundly misshaped (cerebriform) nucleus. 4. TEM of a hairy cell. Arrow indicates a ribosome-lamella complex. This structure is not specific for hairy cell leukemia but is found in a variable proportion of hairy cells in about 50 percent of cases examined by TEM. Frequent cytoplasmic membrane, "hairy," projections. 5. TEM of plasmablast (undifferentiated myeloma cell). Arrow points to a Russell body. 6. A lymphoblast from the marrow of a patient with acute lymphoblastic leukemia. Very high nuclear-to-cytoplasmic ratio. Prominent nucleolus. The nucleus is virtually all euchromatin (likely transcriptionally active). (Reproduced with permission from Lichtman's Atlas of Hematology, www.accessmedicine.com.)