RT Book, Section
A1 Khan, Khurum
A1 Seymour, Matthew
A1 Ring, Alistair
A1 Johnson, Peter
A2 Ring, Alistair
A2 Harari, Danielle
A2 Kalsi, Tania
A2 Mansi, Janine
A2 Selby, Peter
SR Print(0)
ID 1152357696
T1 Clinical Trials in Older Patients with Cancer
T2 Problem Solving in Older Cancer Patients
YR 2018
FD 2018
PB Clinical Publishing
PP New York, NY
SN 9781846921100
LK hemonc.mhmedical.com/content.aspx?aid=1152357696
RD 2021/02/25
AB Clinical  trials  are  conducted  in  patients  with  cancer  in  order  to  determine  the  optimal  treatment  for  a  patient  population.  This  might  include  evaluation  of  a  new  therapeutic  agent,  best  use  of  an  existing  drug  or  intervention,  assessment  of  safety,  or  identification  of  which  patients  are  most  likely  to  benefit  from  treatment.1  The  information  gained  from  such  studies  may  be  submitted  to  regulatory  authorities  and  inform  best  practice  guidelines,  and  will  often  be  required  to  make  decisions  on  whether  an  intervention  may  be  funded  by  those  commissioning  healthcare.  However,  a  unifying  feature  of  these  applications  of  clinical  trial  results  is  that  the  evidence  base  is  established  in  a  population  that  is  representative  of  the  population  we  are  planning  to  treat.  Unfortunately,  this  is  not  necessarily  the  case  when  considering  the  care  of  older  patients  with  cancer.2