RT Book, Section A1 Aster, Jon C. A1 DeAngelo, Daniel J. A2 Aster, Jon C. A2 Bunn, H. Franklin SR Print(0) ID 1175525489 T1 Acute Leukemias T2 Pathophysiology of Blood Disorders, 2e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9781259642067 LK hemonc.mhmedical.com/content.aspx?aid=1175525489 RD 2024/03/28 AB LEARNING OBJECTIVESAfter studying this chapter, you should understand:The pathogenic role of mutations in genes encoding transcription factors and signaling molecules in acute leukemia.The diagnostic and prognostic role of immunophenotyping, cytogenetics, and molecular genetics in acute leukemia.The general approach to treatment of patients with acute leukemia and the associated short-term complications.The unique role of “differentiating” agents in the treatment of acute promyelocytic leukemia.