RT Book, Section
A1 Green, Ralph
A1 Mitra, Ananya Datta
A2 Kaushansky, Kenneth
A2 Prchal, Josef T.
A2 Burns, Linda J.
A2 Lichtman, Marshall A.
A2 Levi, Marcel
A2 Linch, David C.
SR Print(0)
ID 1178740814
T1 Anemia Resulting from Other Nutritional Deficiencies
T2 Williams Hematology, 10e
YR 2021
FD 2021
PB McGraw-Hill Education
PP New York, NY
SN 9781260464122
LK hemonc.mhmedical.com/content.aspx?aid=1178740814
RD 2024/04/23
AB SUMMARYThe  anemia  that  results  from  deficiencies  of  vitamin  B12,  folic  acid  (Chap.  42),  or  iron  (Chap.  44)  are,  in  general,  clearly  defined  and  are  relatively  common.  In  contrast,  the  characteristics  of  anemia  that  may  occur  with  deficiencies  of  other  micronutrients,  such  as  some  of  the  other  vitamins  and  minerals,  are  poorly  defined  and  relatively  rare  in  humans.  When  present,  they  usually  exist  not  as  isolated  deficiencies  of  one  vitamin  or  one  mineral  but  rather  as  a  combination  of  deficiencies  resulting  from  malnutrition  or  malabsorption.  In  this  context,  it  is  difficult  to  deduce  which  abnormalities  are  a  result  of  which  deficiency.  Studies  in  experimental  animals  may  not  accurately  reflect  the  role  of  micronutrients  in  humans.  Accordingly,  our  knowledge  of  the  effect  of  many  micronutrients  on  hematopoiesis  is  fragmentary  and  based  on  clinical  observations  and  interpretations  that  may  be  flawed.  Inborn  metabolic  errors  that  affect  single  micronutrient  pathways  may  shed  light  on  the  specific  effects  of  those  micronutrients  on  hematopoiesis.  The  levels  normally  found  in  the  serum,  red  cell,  and  leukocytes  are  shown  in  Table  45–1.