RT Book, Section A1 Herrmann, Paul C. A2 Kaushansky, Kenneth A2 Prchal, Josef T. A2 Burns, Linda J. A2 Lichtman, Marshall A. A2 Levi, Marcel A2 Linch, David C. SR Print(0) ID 1178742313 T1 Erythrocyte Disorders as a Result of Toxic Agents T2 Williams Hematology, 10e YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260464122 LK hemonc.mhmedical.com/content.aspx?aid=1178742313 RD 2024/10/13 AB SUMMARYErythrocyte disorders can be caused by a wide variety of toxic agents. Whereas some erythrocyte toxins damage red blood cells through well-defined mechanisms, others have mechanisms that are incompletely defined or for which there is complexity involving multiple simultaneous pathways. The well-defined mechanisms include neocytolysis, damage from oxidation, damage to structural proteins, damage to erythrocyte membranes, and direct damage to metabolic pathways. Incompletely defined mechanisms are responsible for toxicity from nanoparticles and metals with broad biological activity spectra such as lead. A table of other toxins not specifically described in the text is included.