RT Book, Section
A1 Kaushansky, Kenneth
A2 Kaushansky, Kenneth
A2 Prchal, Josef T.
A2 Burns, Linda J.
A2 Lichtman, Marshall A.
A2 Levi, Marcel
A2 Linch, David C.
SR Print(0)
ID 1178754257
T1 Thrombocytopenia
T2 Williams Hematology, 10e
YR 2021
FD 2021
PB McGraw-Hill Education
PP New York, NY
SN 9781260464122
LK hemonc.mhmedical.com/content.aspx?aid=1178754257
RD 2024/04/24
AB SUMMARYThrombocytopenia  is  one  of  the  most  frequent  causes  for  hematologic  consultation  in  the  practice  of  medicine  and  may  be  life  threatening.  Although  the  normal  platelet  count  in  humans  (150–400  ×  109/L)  far  exceeds  the  minimal  level  required  to  avoid  pathologic  hemorrhage  (<50  ×  109/L),  a  number  of  medical  conditions  either  increasing  the  destruction  of  platelets  or  reducing  their  production  enhance  the  risk  of  bleeding.  This  chapter  discusses  an  approach  to  the  diagnosis  of  thrombocytopenia,  grouping  various  causes  by  mechanism  of  action  and  describing  our  current  understanding  of  the  pathogenesis,  treatment,  and  prognosis.  In  the  vast  majority  of  patients,  a  cause  of  thrombocytopenia  can  be  identified  and  effective  therapy  instituted.