RT Book, Section A1 Koritzinsky, Marianne A1 Bratman, Scott V. A2 Harrington, Lea A. A2 Tannock, Ian F. A2 Hill, Richard P. A2 Cescon, David W. SR Print(0) ID 1179324987 T1 Molecular and Cellular Basis of Radiotherapy T2 The Basic Science of Oncology, 6e YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781259862076 LK hemonc.mhmedical.com/content.aspx?aid=1179324987 RD 2024/04/25 AB Since their discovery by Roentgen more than a century ago, x-rays have played a major role in modern medicine. The first recorded use of x-rays for the treatment of cancer occurred within 1 year of their discovery. Subsequently, there has been intensive study of x-rays and other ionizing radiations, and their clinical application to cancer treatment has become increasingly sophisticated. This chapter and Chapter 16 review the biological effects of ionizing radiation and the application of that knowledge to cancer treatment.