RT Book, Section A1 Levi, Marcel A1 Kaushansky, Kenneth A2 Kaushansky, Kenneth A2 Prchal, Josef T. A2 Burns, Linda J. A2 Lichtman, Marshall A. A2 Levi, Marcel A2 Linch, David C. SR Print(0) ID 1180468130 T1 Classification, Clinical Manifestations, and Evaluation of Disorders of Hemostasis T2 Williams Hematology, 10e YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781260464122 LK hemonc.mhmedical.com/content.aspx?aid=1180468130 RD 2024/03/28 AB SUMMARYEvaluation of a hemostatic disorder is commonly initiated when (a) a patient or referring physician suspects a bleeding tendency, (b) a bleeding tendency is discovered in one or more family members, (c) an abnormal coagulation assay result is obtained from an individual as part of a routine examination, (d) an abnormal assay result is obtained from a patient during preparation for surgery, or (e) a patient has unexplained diffuse bleeding during or after surgery, during critical illness, or after trauma. Evaluation of a possible hemostatic disorder in each of these scenarios is a stepwise process that requires knowledge of the various classes of hemostatic disorders commonly found under the patient’s particular circumstances. The patient’s history, the results of a physical examination, and an initial set of hemostatic tests usually enable a tentative diagnosis. However, more specific tests are commonly necessary to make a definitive diagnosis. This chapter reviews the necessary steps.