RT Book, Section A1 Killie, Amy A1 Richards, Jonica A1 Varin-Tremblay, Camille A1 Brierley, Karina L. A2 Llor, Xavier A2 Hofstatter, Erin Wysong SR Print(0) ID 1182364959 T1 Principles of Cancer Risk Assessment and Genetic Counseling T2 Cancer Genetics: A Clinical Approach YR 2022 FD 2022 PB McGraw Hill PP New York, NY SN 9781260440270 LK hemonc.mhmedical.com/content.aspx?aid=1182364959 RD 2024/03/28 AB It is estimated that ~5% to 10% of all cancers are hereditary, meaning that they developed largely as a result of a germline mutation in a cancer predisposition gene. Rapidly evolving genetic technology is increasingly allowing for tailored cancer therapy, screening, and risk reduction for individuals with an inherited cancer predisposition. Essential steps in ensuring the realization of the promise of personalized medicine include appropriate risk assessment, development of a management plan, patient education, and facilitation of patient coping. This chapter describes the essential elements of the traditional process of cancer genetic counseling and risk assessment, including the intake and collection of personal and family medical history, risk assessment, informed consent, genetic testing, and psychosocial assessment. However, the field of hereditary cancer genetic counseling and testing has changed significantly over the past decade with rapidly increasing demand and concerns about access to genetic counseling and testing. This changing landscape has led to the proposal and implementation of various alternative care delivery models which often preserve at least some of the elements of the traditional process yet may utilize a differing order, importance, delivery method, and providers of these elements. Identified barriers to access, as well as some alternative care delivery models, will also be introduced in this chapter.