RT Book, Section A1 Herrmann, Paul C. A2 Prchal, Josef T. A2 Lichtman, Marshall A. SR Print(0) ID 1184013157 T1 Erythrocyte Disorders as a Result of Toxic Agents T2 Williams Hematology The Red Cell and Its Diseases YR 2022 FD 2022 PB McGraw Hill PP New York, NY SN 9781264269075 LK hemonc.mhmedical.com/content.aspx?aid=1184013157 RD 2024/03/29 AB SUMMARYErythrocyte disorders can be caused by a wide variety of toxic agents. Whereas some erythrocyte toxins damage red blood cells through well-defined mechanisms, others have mechanisms that are incompletely defined or for which there is complexity involving multiple simultaneous pathways. The well-defined mechanisms include neocytolysis, damage from oxidation, damage to structural proteins, damage to erythrocyte membranes, and direct damage to metabolic pathways. Incompletely defined mechanisms are responsible for toxicity from nanoparticles and metals with broad biological activity spectra such as lead. A table of other toxins not specifically described in the text is included.