RT Book, Section
A1 Layman, Rachel M.
A2 Kantarjian, Hagop M.
A2 Wolff, Robert A.
A2 Rieber, Alyssa G.
SR Print(0)
ID 1190836697
T1 Special Situations in Breast Cancer
T2 The MD Anderson Manual of Medical Oncology, 4e
YR 2022
FD 2022
PB McGraw Hill Education
PP New York, NY
SN 9781260467642
LK hemonc.mhmedical.com/content.aspx?aid=1190836697
RD 2024/04/23
AB KEY  CONCEPTSManagement  of  pregnancy-associated  breast  cancer  requires  careful  multidisciplinary  care  and  coordination  for  optimal  outcomes.Pregnancy  after  a  breast  cancer  diagnosis  is  not  associated  with  worsened  outcomes,  based  on  retrospective  data.Male  breast  cancer  management  is  largely  extrapolated  from  data  on  female  breast  cancer;  however,  tamoxifen  is  the  preferred  endocrine  therapy  agent.Combined  hormone  replacement  therapy  with  estrogen  and  progesterone  in  postmenopausal  women  increases  the  risk  of  developing  breast  cancer,  but  risk  is  not  clearly  increased  with  estrogen-only  therapy.Adjuvant  endocrine  therapy  with  tamoxifen  or  an  aromatase  inhibitor  can  be  considered  for  estrogen  receptor–positive  ductal  carcinoma  in  situ.Patients  with  pathogenic  mutations  in  breast  cancer  susceptibility  genes  should  be  counseled  regarding  the  risks  and  benefits  of  screening  and  prevention  options.