RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Linch, David C. SR Print(0) ID 1189333416 T1 Hemolytic Anemia Resulting from a Chemical or Physical Agent T2 Williams Manual of Hematology, 10e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269204 LK hemonc.mhmedical.com/content.aspx?aid=1189333416 RD 2024/03/28 AB Hemolysis can be mainly intravascular (ie, hypotonic lysis or heat damage) or predominantly extravascular (ie, arsine gas and oxygen).Certain drugs can induce hemolysis in individuals with abnormalities of erythrocytic enzymes, such as glucose-6-phosphate dehydrogenase, or with an unstable hemoglobin (see Chaps. 14 and 17). Such drugs can also cause hemolysis in normal individuals if given in sufficiently large doses.Other drugs induce hemolytic anemia through an immunologic mechanism (see Chap. 24).The drugs and chemicals discussed here cause hemolysis by other mechanisms.