RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Linch, David C. SR Print(0) ID 1189333952 T1 Eosinophils and Their Disorders T2 Williams Manual of Hematology, 10e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269204 LK hemonc.mhmedical.com/content.aspx?aid=1189333952 RD 2024/03/29 AB Eosinophil progenitors originate directly from the common myeloid progenitor after acquisition of interleukin (IL)-5 receptor alpha.Differentiation is regulated by the transcription factors C/EBP-A and GATA-1 in addition to other factors such as GATA-2, PU.1, and FOG-1.The normal adult marrow contains approximately 3% eosinophils.Eosinophils differentiate in the marrow, migrate into the blood, and circulate for 25 hours before entering tissues.