RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Linch, David C. SR Print(0) ID 1189335108 T1 The Mononucleosis Syndromes T2 Williams Manual of Hematology, 10e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269204 LK hemonc.mhmedical.com/content.aspx?aid=1189335108 RD 2024/04/25 AB Infectious mononucleosis is defined as any blood lymphocytosis induced in response to an infectious agent.Usually greater than 50% of the circulating white cells are lymphocytes, more than 10% of which have the morphology of reactive lymphocytes (Figure 53–1).Table 53–1 lists the etiologic agents that produce mononucleosis.Pharyngeal form:— A sore throat is preceded by 1 to 2 weeks of lethargy.— Epstein-Barr virus (EBV) generally is the cause.Glandular form without pharyngitis:— Lymph node enlargement occurs.— The usual cause is an agent other than EBV (eg, Toxoplasma gondii).Typhoidal form:— Lethargy with fever or diarrhea without pharyngitis, usually as a consequence of cytomegalovirus (CMV).