RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Prchal, Josef T.
A1 Levi, Marcel M.
A1 Burns, Linda J.
A1 Linch, David C.
SR Print(0)
ID 1189335698
T1 Mature T-Cell and Natural Killer Cell Lymphomas
T2 Williams Manual of Hematology, 10e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269204
LK hemonc.mhmedical.com/content.aspx?aid=1189335698
RD 2024/04/18
AB The  term  peripheral  T-cell  lymphoma  (PTCL)  refers  to  lymphomas  originating  in  a  mature  (ie,  post-thymic)  T  cell.PTCLs  make  up  10%  to  15%  of  all  non-Hodgkin  lymphomas  and  represent  28  heterogeneous  diseases  as  currently  classified.Table  67–1  lists  the  mature  T-cell  and  natural  killer  (NK)  cell  lymphomas  excluding  primary  cutaneous  lymphoma.The  four  most  common  entities  make  up  60%  to  65%  of  cases  in  the  United  States  and  northern  Europe;  these  are  PTCL  not  otherwise  specified  (PTCL-NOS),  angioimmunoblastic  T-cell  lymphoma  (AITL),  anaplastic  lymphoma  kinase  positive  (ALK+)  anaplastic  large-cell  lymphoma  (ALCL),  and  ALK-negative  ALCL.The  incidence  of  various  types  of  PTCL  varies  widely  based  on  geography  (Table  67–2).