RT Book, Section A1 Lichtman, Marshall A. A1 Kaushansky, Kenneth A1 Prchal, Josef T. A1 Levi, Marcel M. A1 Burns, Linda J. A1 Linch, David C. SR Print(0) ID 1189336645 T1 Disseminated Intravascular Coagulation T2 Williams Manual of Hematology, 10e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269204 LK hemonc.mhmedical.com/content.aspx?aid=1189336645 RD 2024/04/17 AB Disseminated intravascular coagulation (DIC) is a syndrome that is characterized by systemic intravascular activation of coagulation, leading to fibrin deposition in the microvasculature and small and mid-size vessels, thereby contributing to organ dysfunction. Simultaneously, ongoing consumption of platelets and coagulation factors leads to thrombocytopenia and impaired coagulation and may result in serious bleeding complications.DIC never occurs by itself but is always secondary to an underlying cause. Table 86–1 lists the most frequently occurring disorders know to be associated with DIC.