RT Book, Section
A1 Lichtman, Marshall A.
A1 Kaushansky, Kenneth
A1 Prchal, Josef T.
A1 Levi, Marcel M.
A1 Burns, Linda J.
A1 Linch, David C.
SR Print(0)
ID 1189336839
T1 Venous Thromboembolism
T2 Williams Manual of Hematology, 10e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264269204
LK hemonc.mhmedical.com/content.aspx?aid=1189336839
RD 2024/04/23
AB Venous  thromboembolism  (deep  venous  thrombosis  and/or  pulmonary  embolism)  is  a  common  disorder,  which  is  estimated  to  affect  900,000  patients  each  year  in  the  United  States.Pulmonary  embolism  may  cause  sudden  or  abrupt  death,  underscoring  the  importance  of  prevention  as  the  critical  strategy  for  reducing  death  from  pulmonary  embolism.Of  the  estimated  600,000  cases  of  nonfatal  venous  thromboembolism  in  the  United  States  each  year,  approximately  60%  present  clinically  as  deep  venous  thrombosis  and  40%  present  as  pulmonary  embolism.Most  clinically  important  pulmonary  emboli  arise  from  proximal  deep  venous  thrombosis  (thrombosis  involving  the  popliteal,  femoral,  or  iliac  veins).  Upper  extremity  deep  venous  thrombosis  also  may  lead  to  clinically  important  pulmonary  embolism.  Other  less  common  sources  of  pulmonary  embolism  include  the  deep  pelvic  veins,  renal  veins,  inferior  vena  cava,  right  side  of  the  heart,  and  axillary  veins.Acquired  and  inherited  risk  factors  for  venous  thromboembolism  have  been  identified  (Table  90–1).  (For  inherited  thrombophilia,  see  Chap.  89.)  The  risk  of  thromboembolism  increases  when  more  than  one  predisposing  factor  is  present.