RT Book, Section A1 Levin, Ellis R. A1 Vitek, Wendy S. A1 Hammes, Stephen R. A2 Brunton, Laurence L. A2 Knollmann, Björn C. SR Print(0) ID 1193236825 T1 Estrogens, Progestins, and the Female Reproductive Tract T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264258079 LK hemonc.mhmedical.com/content.aspx?aid=1193236825 RD 2024/10/07 AB Estrogens and progestins are endogenous hormones that produce numerous physiological actions. In women, these include developmental effects, neuroendocrine actions involved in the control of ovulation, the cyclical preparation of the reproductive tract for fertilization and implantation, and major actions on mineral, carbohydrate, protein, and lipid metabolism. Estrogens also have important actions in males, including effects on bone, spermatogenesis, and behavior. Well-characterized receptors for each hormone mediate biological actions in both the unliganded and the liganded states.