RT Book, Section A1 O’Donnell, James M. A1 Bies, Robert R. A1 Williams, Aislinn J. A2 Brunton, Laurence L. A2 Knollmann, Björn C. SR Print(0) ID 1193229416 T1 Drug Therapy of Depression and Anxiety Disorders T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264258079 LK hemonc.mhmedical.com/content.aspx?aid=1193229416 RD 2024/10/07 AB Depression and anxiety disorders are the most common mental illnesses, each affecting in excess of 15% of the population at some point in the life span. With the advent of more selective and safer drugs, the use of antidepressants and anxiolytics has moved from the exclusive domain of psychiatry to primary care and other medical specialties. The relative safety of the majority of commonly used antidepressants and anxiolytics notwithstanding, their optimal use requires a clear understanding of their mechanisms of action, pharmacokinetics, adverse effects, potential drug interactions, and the differential diagnosis of psychiatric illnesses (Thronson and Pagalilauan, 2014).