RT Book, Section
A1 Keiser, Jennifer
A1 McCarthy, James
A1 Hotez, Peter
A2 Brunton, Laurence L.
A2 Knollmann, Björn C.
SR Print(0)
ID 1193241382
T1 Chemotherapy of Helminth Infections
T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition
YR 2023
FD 2023
PB McGraw-Hill Education
PP New York, NY
SN 9781264258079
LK hemonc.mhmedical.com/content.aspx?aid=1193241382
RD 2024/04/20
AB Helminths  are  invertebrates  featuring  elongated,  flat  or  round  bodies.  According  to  their  morphology  and  the  host  organ  they  inhabit,  they  are  classified  as  flatworms  or  platyhelminths,  which  include  flukes  (lung  flukes  [Paragonimus  spp.],  liver  flukes  [Fasciola  spp.,  Clonorchis  sinensis,  Opisthorchis  spp.],  intestinal  flukes,  or  blood  flukes  [Schistosoma  spp.]),  tapeworms  (cestodes  [including  Taenia  solium,  T.  saginata],  Diphyllobothrium  latum,  Hymenolepis  nana,  and  Echinococcus  spp.),  and  roundworms  (nematodes).  The  nematodes  of  major  medical  importance  include  the  soil-transmitted  helminths  (STHs)  (Ascaris  lumbricoides,  Trichuris  trichiura,  Necator  americanus,  Ancylostoma  duodenale,  Strongyloides  stercoralis)  and  the  filarial  worms.  Lymphatic  filariasis  is  caused  by  Wuchereria  bancrofti,  Brugia  malayi,  and  Brugia  timori.  Subcutaneous  filariasis  is  caused  by  Loa  loa,  Mansonella  streptocerca,  and  Onchocerca  volvulus.  Mansonella  perstans  and  Mansonella  ozzardi  are  the  causative  helminths  for  serous  cavity  filariasis.