RT Book, Section A1 Salani, Ritu A1 Nagel, Christa A2 Karlan, Beth Y. A2 Bristow, Robert E. A2 Li, Andrew J. SR Print(0) ID 1106570746 T1 Management of the Adnexal Mass T2 Gynecologic Oncology: Clinical Practice and Surgical Atlas YR 2015 FD 2015 PB McGraw-Hill Medical PP New York, NY SN 9780071749268 LK hemonc.mhmedical.com/content.aspx?aid=1106570746 RD 2024/10/14 AB Uterine adnexae are defined as the areas adjacent to the uterus that are occupied by the fallopian tubes and ovaries. The embryologic origin of the fallopian tubes and ovaries are 2 distinct events in the development of a female embryo. Development of the ovaries begins before the development of the remainder of the genital tract. The origin of the male and female gonads are similar up until the seventh week of gestation, at which time the primitive sex cords begin to break up in the female embryo. The developing ovary eventually has 3 layers: the surface epithelium, primitive germ cells, and sex cord epithelium. These layers give rise to the 3 main types of ovarian tumors: (1) epithelial tumors, which comprise approximately 70% of all ovarian neoplasms; (2) germ cell tumors, which comprise 15% to 20% of ovarian tumors; and (3) sex cord–stromal tumors, which account for 5% to 10% of ovarian tumors. The remainder of the masses are a result of metastatic or secondary involvement to the ovary.1