RT Book, Section
A1 Herrmann, Paul C.
A2 Kaushansky, Kenneth
A2 Lichtman, Marshall A.
A2 Prchal, Josef T.
A2 Levi, Marcel M.
A2 Press, Oliver W.
A2 Burns, Linda J.
A2 Caligiuri, Michael
SR Print(0)
ID 1121094386
T1 Erythrocyte Disorders as a Result of Chemical and Physical Agents
T2 Williams Hematology, 9e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071833004
LK hemonc.mhmedical.com/content.aspx?aid=1121094386
RD 2024/04/16
AB SUMMARYErythrocyte  disorders  from  physical  or  chemical  agents  occur  via  such  processes  as  red  cell  volume  expansion  within  hypotonic  solutions,  erythrocyte  membrane  damage  from  biotoxins,  damage  to  the  spectrin  skeleton  from  insults  such  as  heat,  and  eryptosis  associated  with  oxidizing  agents  such  as  oxygen,  arsine  gas,  and  chlorates.  Erythrocyte  damage  also  can  be  induced  by  other  agents  that  lack  well  defined  mechanisms  of  action  (see  Table  52–1).  These  processes  include  erythrocyte  damage  caused  by  lead,  copper,  and  radiation,  as  well  as  neocytolysis,  a  phenomenon  once  thought  unique  to  microgravity,  but  subsequently  observed  in  individuals  demonstrating  altitude  induced  polycythemia  upon  transition  to  normoxic  conditions.